RBM3 PROMOTES NEUROGENESIS IN A NICHE-DEPENDENT MANNER VIA IMP2-IGF2 SIGNALING PATHWAY AFTER HYPOXIC-ISCHEMIC BRAIN INJURY

RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury

Therapeutic hypothermia is a potent tool in the treatment of neonatal hypoxic-ischemic (HI) injury, yet the underlying mechanisms remain unclear.Here, authors demonstrate how the RNA-binding motif Western Boots protein RBM3, which is induced by mild Windshield Headers cooling while global translation rate is slowed down, contributes substantially t

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The life imprisonment in the Hungarian criminal law

Among penalties, the imprisonment is imposed for a fixed duration or for a life term in Hungary.In many cases the duration of an imprisonment may be longer due to the fact that relative dangerous criminal offenses or special circumstances shall be punished differently.As a part of the imprisonment system, but above and on the top of the penalties t

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The Interaction Between Microorganisms, Metabolites, and Immune System in the Female Genital Tract Microenvironment

The female reproductive tract microenvironment includes microorganisms, metabolites, and immune components, and the balance of the interactions among them plays an important role in maintaining female reproductive tract homeostasis and health.When any one of the reproductive tract microorganisms, metabolites, or immunity is out of balance, it will

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ESM1 promote proliferation, invasion and angiogenesis via Akt/mTOR and Ras pathway in kidney renal clear cell carcinoma

Abstract The most common types of renal carcinoma is kidney renal clear cell carcinoma (KIRC).ESM1 is a secreted protein, which involved in, lipids and glucose metabolism, but their role in angiogenesis is contradictory in different disease, especially in KIRC.Bioinformatic analysis confirmed the ESM1 expression and prognosis in KIRC.IHC staining r

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